Bromine → HCID 14985977, compound

Participants

Reaction Steps

To a solution of 1.4 g (0.00585 mol) of 7-methanesulfonamido-1-tetralone in 20 mL of methylene chloride was added dropwise a solution of 0.94 g (0.0059 mol) of bromine in 5 mL of methylene chloride. The progress of the reaction was followed by thin layer chromatography (fl. silica gel/CH2Cl2). A few additional drops of the bromine solution were added to completely consume the starting material. The solution was evaporated to dryness to give 2.0 g of 2-bromo-7-methanesulfonamido-1-tetralone, mp 87°-92° C.

Provenance & Evidence