Sodium triacetoxyborohydride → 5-{4-[2-(5-Bromo-2-fluorophenyl)ethyl]-1-piperazinyl}-2-methylquinoline

Beteiligte Stoffe

Rolle	Name	HCID	Einwaage
Edukt	Sodium triacetoxyborohydride	HCID 5049666	—
Edukt	2-Methyl-5-piperazin-1-yl-quinoline	HCID 49851901	—
Edukt	2-(5-Bromo-2-fluorophenyl)acetaldehyde	HCID 57444351	—
Produkt	5-{4-[2-(5-Bromo-2-fluorophenyl)ethyl]-1-piperazinyl}-2-methylquinoline	HCID 57444350	95%

Reaktionsschritte

The title compound was prepared in 95% yield from (5-bromo-2-fluorophenyl)acetaldehyde (0.98 g), 2-methyl-5-(1-piperazinyl)quinoline (0.51 g) and sodium triacetoxyborohydride (0.95 g) according to the procedure described for Example 131.

Herkunft & Nachweise

DOI	10.6084/m9.figshare.5104873.v1
Patentnummer	US07732600B2
Quelldatensatz	uspto-grants-2010_06
ORD ID	ord-9ce384b7d09043c1826833923aa19bef
Quellennotiz	uspto-grants-2010_06