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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1586833Generated: October 31, 2026

HCID 178435606, compound → HCID 178439914, compound

https://huagongshe.com/reaction/1586833

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHCID 178435606HCID 178435606—
CatalystPalladiumHCID 23938—
SolventMethanolHCID 887—
ProductHCID 178439914HCID 178439914—

Reaction Steps

A mixture of 7-methyl-2-propyl-3-[4-[2-(1H-tetrazol-5-yl)-4-vinyl-1-pyrrolyl]benzyl]-3H-imidazo[4,5-b]pyridine (40 mg), 10% palladium on carbon (10 mg) and methanol (5 ml) was stirred at room temperature for 4 hours under hydrogen atmosphere (3 atm). After filtration, the filtrate was evaporated in vacuo. The residue was purified by preparative thin layer chromatography (dichloromethane:methanol=5:1) to give 3-[4-[4-ethyl-2-(1H-tetrazol-5-yl)-1-pyrrolyl]benzyl]-7-methyl-2-propyl-3H-imidazo[4,5-b]pyridine (20 ml).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS05215994
Source datasetuspto-grants-1993_06
ORD IDord-6e14317c591e4cdaa9b9e28d24759f29
Source noteuspto-grants-1993_06