Sodium Hydroxide → HCID 19008520, compound

HRID 1586879Notes

Reaction equation

HRID 1586879 reaction equation
[C:1]1([S:11]([OH:13])=[O:12])[C:10]2[C:5](=[CH:6][CH:7]=[CH:8][CH:9]=2)[CH:4]=[CH:3][CH:2]=1.[OH-].[Na+].[CH:16]([S:18](Cl)(=[O:20])=[O:19])=[CH2:17]>O.C(#N)C>[CH:16]([S:18](=[O:20])(=[O:19])[S:11]([C:1]1[C:10]2[C:5](=[CH:6][CH:7]=[CH:8][CH:9]=2)[CH:4]=[CH:3][CH:2]=1)(=[O:13])=[O:12])=[CH2:17]

Participants

6

Reactant 3

HCID 14798Sodium HydroxideHCID 5334456608-47-5HCID 108887691-Naphthalenesulfinic acid

Product 1

HCID 19008520HCID 19008520, compoundYield 24.9%

Reagents, catalysts & solvents 2

HCID 962WaterSolvent3×HCID 6342AcetonitrileSolvent

Procedure

15 ml of water was added to 9.6 g of 1-naphthalene sulfinic acid and a solution of 2 g of sodium hydroxide in 5 ml of water was added to the mixture. To the solution there was added a solution of 6.3 g of vinylsulfonyl chloride in 20 ml of acetonitrile at room temperature with stirring and the mixture was stirred at room temperature for additional 24 hours. The reaction solution was poured into 300 ml of water, the resulting precipitates were recovered through filtration and recrystallized from a mixed solvent of benzene and ethanol to give 3.5 g of vinyl-1-naphthyldisulfone.

Workup

  1. stirringthe mixture was stirred at room temperature for additional 24 hours
  2. customthe resulting precipitates
  3. filtrationwere recovered through filtration
  4. customrecrystallized from a mixed solvent of benzene and ethanol

Sources & evidence

ORD record
ord-ef3aa95e744f47fdb97902e8ad05518b
Source dataset
uspto-grants-1993_06
Patent number
US05216105

Reaction notes

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