HuagongsheHuagongshe Chemistry Print Report · For research reference only
Sodium borohydride → 4-(2-Hydroxyethoxy)-6,6'-dimethyl-2,2'-bipyridine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Sodium borohydride | HCID 4311764 | — |
| Reactant | 4-(2-hydroxyethoxy)-6,6'-dimethyl-2,2'-bipyridine-N-oxide | HCID 19760122 | — |
| Catalyst | Palladium | HCID 23938 | — |
| Solvent | Methanol | HCID 887 | — |
| Product | 4-(2-Hydroxyethoxy)-6,6'-dimethyl-2,2'-bipyridine | HCID 19760117 | — |
Reaction Steps
4-(2-hydroxyethoxy)-6,6'-dimethyl-2,2'-bipyridine-N-oxide (23) (2.40 g, 9.22 mmoles) was dissolved in methanol (75 ml). 10% palladium on carbon (0.54 g) was added and then slowly sodium borohydride (3.24 g, 85.6 mmoles). Palladium on carbon was filtered out and the solvent was evaporated. The product was purified by means of flash chromatography (silica, 5-50% methanol/chloroform).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05216134 |
| Source dataset | uspto-grants-1993_06 |
| ORD ID | ord-50da65f52c124b6ea43302440c8aaecf |
| Source note | uspto-grants-1993_06 |