Ethanol → L-Lysine ethyl ester

HRID 1586935Notes

Reaction equation

HRID 1586935 reaction equation
S(Cl)(Cl)=O.Cl.[NH2:6][C@H:7]([C:13]([OH:15])=[O:14])[CH2:8][CH2:9][CH2:10][CH2:11][NH2:12].[CH2:16](O)[CH3:17]>>[CH2:16]([O:14][C:13](=[O:15])[C@H:7]([CH2:8][CH2:9][CH2:10][CH2:11][NH2:12])[NH2:6])[CH3:17]

Participants

4

Reactant 3

HCID 702EthanolHCID 24386Thionyl ChlorideHCID 69568L-Lysine monohydrochloride

Product 1

HCID 107469L-Lysine ethyl ester

Procedure

Thionyl chloride (5.0 ml, 8.06 g, 68 mmoles) was dropped into 500 ml of icecooled dry ethanol. The stirred mixture was kept for 20 min at this temperature and L-lysine hydrochloride (20 g, 109 mmoles) was added.

Workup

  1. additionwas added

Sources & evidence

ORD record
ord-8457eda53cf942439033171f3359fcc3
Source dataset
uspto-grants-1993_06
Patent number
US05216134

Reaction notes

Loading…