HuagongsheHuagongshe Chemistry Print Report · For research reference only
Phosphorus oxychloride → 2,5-Diamino-4,6-dichloropyrimidine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Phosphorus oxychloride | HCID 24813 | — |
| Reactant | HCID 178479162 | HCID 178479162 | — |
| Catalyst | Tetraethylammonium Chloride | HCID 5946 | — |
| Product | 2,5-Diamino-4,6-dichloropyrimidine | HCID 301039 | 50% |
Reaction Steps
Dry 2,5-Diamino-4,6-dihydroxypyrimidine hydrochloride (1.8 g), tetraethyl ammonium chloride (9.8 g) (dry) and phosphorus oxychloride (5.5 ml) were heated at 105° for 20 hours. The reaction mixture was processed as in Example 1 on a smaller scale to give 0.9 g (50% yield) 2,5-diamino-4,6-dichloropyrimidine.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05216161 |
| Source dataset | uspto-grants-1993_06 |
| ORD ID | ord-3c739de22eb046e492be0d642f82cb2b |
| Source note | uspto-grants-1993_06 |