HuagongsheHuagongshe Chemistry Print Report · For research reference only
Phosphorus oxychloride → 2,5-Diamino-4,6-dichloropyrimidine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Phosphorus oxychloride | HCID 24813 | — |
| Reactant | HCID 15935269 | HCID 15935269 | — |
| Reactant | HCID 178479162 | HCID 178479162 | — |
| Product | 2,5-Diamino-4,6-dichloropyrimidine | HCID 301039 | 65% |
Reaction Steps
Dry 2,5-Diamino-4,6-dihydroxypyrimidine hydrochloride (3.6 g), dry N-ethyl-N-methyl piperidinium chloride (22 g) and phosphorus oxychloride (13 ml) were heated at 105° with stirring for 24 hours. The reaction mixture was processed as in Example 1 to give 2.27 g (65% yield) of 2,5-diamino-4,6-dichloropyrimidine.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05216161 |
| Source dataset | uspto-grants-1993_06 |
| ORD ID | ord-b471ffe0439241508ca452f13b8e7d04 |
| Source note | uspto-grants-1993_06 |