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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 15870Generated: October 26, 2026

Methanesulfonamide → N-(4-Fluoro-3-{2-[4-(2-methyl-5-quinolinyl)-1-piperazinyl]ethyl}phenyl)methanesulfonamide

https://huagongshe.com/reaction/15870

Reaction equation

Participants

RoleNameHCIDCharge
ReactantMethanesulfonamideHCID 72879—
Reactant5-{4-[2-(5-Bromo-2-fluorophenyl)ethyl]-1-piperazinyl}-2-methylquinolineHCID 57444350—
ProductN-(4-Fluoro-3-{2-[4-(2-methyl-5-quinolinyl)-1-piperazinyl]ethyl}phenyl)methanesulfonamideHCID 5744435369%

Reaction Steps

The title compound was prepared in 69% yield according to the general procedure for the preparation of amides, ureas and carbamates (Method A) starting from 5-{4-[2-(5-bromo-2-fluorophenyl)ethyl]-1-piperazinyl}-2-methylquinoline and methanesulfonamide.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07732600B2
Source datasetuspto-grants-2010_06
ORD IDord-05d45e2a3c694c1eb21132310d12dc60
Source noteuspto-grants-2010_06