HCID 18652184, compound → HCID 18652188, compound

Participants

Reaction Steps

A mixture of 12α-benzyloxymethoxy-3α,7α-di-tert-butyldimethylsilyloxy-17β-[(1,1-diphenyl)-1-penten-4-yl]-5β-androstane (4.63 g), 1M zinc chloride in ether (10.5 ml) and ethanethiol (2.0 ml) in ether (10 ml) is stirred at room temperature for about 30 minutes. The mixture is concentrated in vacuo and the residue taken up in ether. The ether solution is washed with water, dried over magnesium sulfate, filtered and concentrated in vacuo to give the desired product.

Provenance & Evidence