Allyl bromide → Ethyl 2-allyloxy-4-[N-{1-(2-piperidino-phenyl)-1-butyl}aminocarbonylmethyl]-benzoate

HRID 1587069Notes

Reaction equation

HRID 1587069 reaction equation
[OH:1][C:2]1[CH:12]=[C:11]([CH2:13][C:14]([NH:16][CH:17]([C:21]2[CH:26]=[CH:25][CH:24]=[CH:23][C:22]=2[N:27]2[CH2:32][CH2:31][CH2:30][CH2:29][CH2:28]2)[CH2:18][CH2:19][CH3:20])=[O:15])[CH:10]=[CH:9][C:3]=1[C:4]([O:6][CH2:7][CH3:8])=[O:5].[CH2:33](Br)[CH:34]=[CH2:35]>>[CH2:35]([O:1][C:2]1[CH:12]=[C:11]([CH2:13][C:14]([NH:16][CH:17]([C:21]2[CH:26]=[CH:25][CH:24]=[CH:23][C:22]=2[N:27]2[CH2:32][CH2:31][CH2:30][CH2:29][CH2:28]2)[CH2:18][CH2:19][CH3:20])=[O:15])[CH:10]=[CH:9][C:3]=1[C:4]([O:6][CH2:7][CH3:8])=[O:5])[CH:34]=[CH2:33]

Participants

3

Reactant 2

HCID 7841Allyl bromideHCID 15227812ethyl 2-hydroxy-4-[N-{1-(2-piperidinophenyl)-1-butyl}-aminocarbonylmethyl]-benzoate

Product 1

HCID 21261811Ethyl 2-allyloxy-4-[N-{1-(2-piperidino-phenyl)-1-butyl}aminocarbonylmethyl]-benzoate

Procedure

Prepared from ethyl 2-hydroxy-4-[N-{1-(2-piperidinophenyl) -1-butyl}-aminocarbonylmethyl]-benzoate, using allyl bromide.

Sources & evidence

ORD record
ord-c0c356007e134063a92f06330fa0ce6c
Source dataset
uspto-grants-1993_06
Patent number
US05216167

Reaction notes

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