HCID 86746907, compound → HCID 86746905, compound

Participants

Reaction Steps

1 g of O-[[2-[(cholest-5-en-3β-yloxy)carbonyloxy]ethoxy]hydroxyphosphinyl]choline hydroxide internal salt is hydrogenated in 100 ml of methanol with 1 g of Pd/C 5% under 30 bar of H2 at 80° C. After filtration the solution is evaporated and the residue is dissolved in chloroform-methanol-dioxan. By adding ether there is obtained 0.6 g of O-[[2-[(5α-cholestan-3β-yloxy)carbonyloxy]ethoxy]hydroxyphosphinyl]choline hydroxide internal salt as a hygroscopic powder, m.p. 225° C.

Provenance & Evidence