HuagongsheHuagongshe Chemistry Print Report · For research reference only
Potassium Carbonate → Methyl 4-amino-3-(4-chlorocinnamylamino)benzoate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Potassium Carbonate | HCID 11430 | — |
| Reactant | 3,5-Diamino-2-methylbenzoic acid | HCID 135524 | — |
| Reactant | p-Chlorocinnamyl chloride | HCID 53728250 | — |
| Solvent | Dimethylformamide | HCID 6228 | — |
| Product | Methyl 4-amino-3-(4-chlorocinnamylamino)benzoate | HCID 53813638 | 63.2% |
Reaction Steps
5.0 g of methyl 3,4-diaminobenzoate was dissolved in 40 ml of dimethylformamide, and to the solution were added 2.07 g of potassium carbonate and 1.87 g of p-chlorocinnamyl chloride, and reaction was carried out according to the procedure in Reference Example 40, to obtain 2.0 g of the title compound as a light brown oil.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05216150 |
| Source dataset | uspto-grants-1993_06 |
| ORD ID | ord-eb77129261bf4835b55627b25a373394 |
| Source note | uspto-grants-1993_06 |