hexanoic acid, 6-amino-, monosodium salt → N-{4,6-Bis[(1-octyloxy-2,2,6,6-tetramethylpiperidin-4-yl)butylamino]-1,3,5-triazin-2-yl}-6-aminohexanoic acid

HRID 1587218Notes

Reaction equation

Cl[C:2]1[N:7]=[C:6]([NH:8][CH2:9][CH2:10][CH2:11][CH2:12][CH:13]2[CH2:18][C:17]([CH3:20])([CH3:19])[N:16]([O:21][CH2:22][CH2:23][CH2:24][CH2:25][CH2:26][CH2:27][CH2:28][CH3:29])[C:15]([CH3:31])([CH3:30])[CH2:14]2)[N:5]=[C:4]([NH:32][CH2:33][CH2:34][CH2:35][CH2:36][CH:37]2[CH2:42][C:41]([CH3:44])([CH3:43])[N:40]([O:45][CH2:46][CH2:47][CH2:48][CH2:49][CH2:50][CH2:51][CH2:52][CH3:53])[C:39]([CH3:55])([CH3:54])[CH2:38]2)[N:3]=1.[NH2:56][CH2:57][CH2:58][CH2:59][CH2:60][CH2:61][C:62]([O-:64])=[O:63].[Na+]>>[CH2:22]([O:21][N:16]1[C:17]([CH3:20])([CH3:19])[CH2:18][CH:13]([CH2:12][CH2:11][CH2:10][CH2:9][NH:8][C:6]2[N:5]=[C:4]([NH:32][CH2:33][CH2:34][CH2:35][CH2:36][CH:37]3[CH2:42][C:41]([CH3:43])([CH3:44])[N:40]([O:45][CH2:46][CH2:47][CH2:48][CH2:49][CH2:50][CH2:51][CH2:52][CH3:53])[C:39]([CH3:54])([CH3:55])[CH2:38]3)[N:3]=[C:2]([NH:56][CH2:57][CH2:58][CH2:59][CH2:60][CH2:61][C:62]([OH:64])=[O:63])[N:7]=2)[CH2:14][C:15]1([CH3:30])[CH3:31])[CH2:23][CH2:24][CH2:25][CH2:26][CH2:27][CH2:28][CH3:29]

Participants

Reactant 2

HCID 23663648hexanoic acid, 6-amino-, monosodium salt

HCID 543136252-chloro-4,6-bis[N-(1-octyloxy-2,2,6,6-tetramethylpiperidin-4-yl)butylamino]-1,3,5-triazine

Product 1

HCID 67849760N-{4,6-Bis[(1-octyloxy-2,2,6,6-tetramethylpiperidin-4-yl)butylamino]-1,3,5-triazin-2-yl}-6-aminohexanoic acid

Procedure

The title compound, a colorless glass, is prepared from 2-chloro-4,6-bis[N-(1-octyloxy-2,2,6,6-tetramethylpiperidin-4-yl)butylamino]-1,3,5-triazine and sodium 6-aminohexanoate according to the procedure of Example 15.

Sources & evidence

ORD record: ord-784b8a87c5ca4e09acfae5dd2671e193
Source dataset: uspto-grants-1993_06
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US05216156

Reaction notes

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