HuagongsheHuagongshe Chemistry Print Report · For research reference only
HCID 14850773, compound → HCID 14850774, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | HCID 14850773 | HCID 14850773 | — |
| Catalyst | Palladium | HCID 23938 | — |
| Solvent | Methanol | HCID 887 | — |
| Product | HCID 14850774 | HCID 14850774 | — |
Reaction Steps
A mixture of 500 mg of 4-(diethylphosphonomethyl)quinoline-2-carboxamide and 1 g of 10% palladium on charcoal in 75 ml of methanol is hydrogenated at 3 atmospheres pressure for 24 hours, filtered and evaporated to dryness. Chromatography on silica gel using methanol/methylene chloride (1:10) as eluent yields cis-4-(diethylphosphonomethyl)-1,2,3,4-tetrahydroquinoline-2-carboxamide.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05217963 |
| Source dataset | uspto-grants-1993_06 |
| ORD ID | ord-7ae6ef94f0b04121aa3128fc5a2928e0 |
| Source note | uspto-grants-1993_06 |