HuagongsheHuagongshe Chemistry Print Report · For research reference only
Ethanol → Ethyl pyridine-4-acetate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Ethanol | HCID 702 | — |
| Reactant | Sulfuric Acid | HCID 1118 | — |
| Reactant | Sodium Carbonate | HCID 10340 | — |
| Reactant | Sodium Hydroxide | HCID 14798 | — |
| Reactant | 4-Pyridineacetic acid | HCID 34228 | — |
| Product | Ethyl pyridine-4-acetate | HCID 736321 | — |
Reaction Steps
A solution of 4-pyridylacetic acid in 500 ml of anhydrous ethanol containing 75 ml of concentrated sulfuric acid is refluxed 18 hours. The solution is cooled to 0° an neutralized by addition of sodium hydroxide solution and saturated aqueous sodium carbonate. Extraction with ethyl acetate yields on concentration in vacuo ethyl 4-pyridylacetate.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05217963 |
| Source dataset | uspto-grants-1993_06 |
| ORD ID | ord-c3f0f62ddd6448b9b27e77531bed5a60 |
| Source note | uspto-grants-1993_06 |