Methyl iodide → HCID 18994385, compound

HRID 1587382Notes

Reaction equation

HRID 1587382 reaction equation
[OH:1][C:2]1([C:8]2[O:9][C:10]([S:13][C:14]3[CH:23]=[CH:22][C:21]4[C:16](=[CH:17][CH:18]=[CH:19][CH:20]=4)[CH:15]=3)=[CH:11][CH:12]=2)[CH2:7][CH2:6][O:5][CH2:4][CH2:3]1.[CH3:24]I>>[CH3:24][O:1][C:2]1([C:8]2[O:9][C:10]([S:13][C:14]3[CH:23]=[CH:22][C:21]4[C:16](=[CH:17][CH:18]=[CH:19][CH:20]=4)[CH:15]=3)=[CH:11][CH:12]=2)[CH2:3][CH2:4][O:5][CH2:6][CH2:7]1

Participants

3

Reactant 2

HCID 6328Methyl iodideHCID 18994410HCID 18994410, compound

Product 1

HCID 18994385HCID 18994385, compoundYield 92%

Procedure

Using the procedure described in Example 1, 4-hydroxy-4-[5-(naphth-2-ylthio)fur-2-yl]tetrahydropyran was reacted with methyl iodide to give 4-methoxy-4-[5-(naphth-2-ylthio)fur-2-yl]tetrahydropyran in 92% yield as an oil.

Sources & evidence

ORD record
ord-98e320437af74de89a601d90e06c7292
Source dataset
uspto-grants-1993_06
Patent number
US05217978

Reaction notes

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