HuagongsheHuagongshe Chemistry Print Report · For research reference only
4,5-Bis(4-methoxyphenyl)-2-hydroxymethylthiazole → 4,5-Bis(4-methoxyphenyl)-2-formylthiazol
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4,5-Bis(4-methoxyphenyl)-2-hydroxymethylthiazole | HCID 10336564 | — |
| Catalyst | HCID 178418406 | HCID 178418406 | — |
| Solvent | Ethyl Acetate | HCID 8857 | — |
| Product | 4,5-Bis(4-methoxyphenyl)-2-formylthiazol | HCID 10381679 | 64.9% |
Reaction Steps
A mixture of 4,5-bis(4-methoxyphenyl)-2-hydroxymethylthiazole (5.04 g) and manganese dioxide (35.0 g) in ethyl acetate (250 ml) was stirred at ambient temperature for 5.5 hours. After filtration, the filtrate was evaporated in vacuo, and the resulting residue was washed with hexane to give 4,5-bis(4-methoxyphenyl)-2-formylthiazol (3.25 g).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05217971 |
| Source dataset | uspto-grants-1993_06 |
| ORD ID | ord-b2cd37ade36846708ae015591742f14c |
| Source note | uspto-grants-1993_06 |