3,4-Dihydroxybenzaldehyde → 3,4-Dihydroxybenzylidenecyanoacethydrazide

HRID 1587457ノート

反応式

HRID 1587457 の反応式
[OH:1][C:2]1[CH:3]=[C:4]([CH:7]=[CH:8][C:9]=1[OH:10])[CH:5]=O.[C:11]([CH2:13][C:14]([NH:16][NH2:17])=[O:15])#[N:12]>C(O)C.N1CCCCC1>[OH:1][C:2]1[CH:3]=[C:4]([CH:7]=[CH:8][C:9]=1[OH:10])[CH:5]=[C:13]([C:11]#[N:12])[C:14]([NH:16][NH2:17])=[O:15]

参加物

5

反応物 2

HCID 87683,4-DihydroxybenzaldehydeHCID 8820Cyanoacetic acid hydrazide

生成物 1

HCID 537220483,4-Dihydroxybenzylidenecyanoacethydrazide収率 50.2%

試薬・触媒・溶媒 2

HCID 8082Piperidine触媒HCID 702Ethanol溶媒

実験手順

To 0.69 g (5 mmol) 3,4-dihydroxybenzaldehyde and 0.55 g (5.5 mmol) cyanoacethydrazide in 40 ml ethanol was added 2 drops piperidine. After 21/2 hours of reflux, the reaction mixture was cooled, filtered and washed with cold ethanol to give 0.55 g (50% yield) of product, an orange solid, m.p. 220° C. (decomposition).

後処理

  1. temperatureAfter 21/2 hours of reflux
  2. temperaturethe reaction mixture was cooled
  3. filtrationfiltered
  4. washwashed with cold ethanol

出典と根拠

ORDレコード
ord-ed1c041786bf46dfb55bb5c14b0a4e16
出典データセット
uspto-grants-1993_06
特許番号
US05217999

反応ノート

読み込み中…