3,5-Bis(tert-butyl)benzaldehyde → alpha-Cyano-beta-(3,5-di-tert butylphenyl)propenethioamide

HRID 1587462Notes

Reaction equation

[C:1]([CH2:3][C:4]([NH2:6])=[S:5])#[N:2].[C:7]([C:11]1[CH:12]=[C:13]([CH:16]=[C:17]([C:19]([CH3:22])([CH3:21])[CH3:20])[CH:18]=1)[CH:14]=O)([CH3:10])([CH3:9])[CH3:8]>>[C:1]([C:3](=[CH:14][C:13]1[CH:12]=[C:11]([C:7]([CH3:9])([CH3:8])[CH3:10])[CH:18]=[C:17]([C:19]([CH3:22])([CH3:21])[CH3:20])[CH:16]=1)[C:4](=[S:5])[NH2:6])#[N:2]

Participants

Reactant 2

HCID 12682533,5-Bis(tert-butyl)benzaldehyde

HCID 14162772-Cyanoethanethioamide

Product 1

HCID 54042770alpha-Cyano-beta-(3,5-di-tert butylphenyl)propenethioamide

Procedure

Following the procedure as set forth in Example 11 above, cyanothioacetamide was condensed with 3,5-di-tert butylbenzaldehyde to yield the title compound, m.p. 172°-174° C.

Sources & evidence

ORD record: ord-f9c8b2d2641c4ccc96fd6e3505584128
Source dataset: uspto-grants-1993_06
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US05217999

Reaction notes

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