Ethanolamine → HCID 61697130, compound

HRID 1587531Notes

Reaction equation

HRID 1587531 reaction equation
[CH2:1]([CH2:3][NH2:4])[OH:2].Br[CH2:6][CH2:7][CH2:8][C:9]#[N:10]>C(O)C>[OH:2][CH2:1][CH2:3][NH:4][CH:8]([CH2:7][CH3:6])[C:9]#[N:10]

Participants

4

Reactant 2

HCID 700EthanolamineHCID 214124-Bromobutyronitrile

Product 1

HCID 61697130HCID 61697130, compound

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent

Procedure

Dissolve ethanolamine (11.3 g, 0.185 mol) and 4-bromobutyronitrile (32.6 g, 0.22 mol) in ethanol (700 mL) and heat at reflux for 18 hours. Evaporate the solvent in vacuo and purify by distillation to give the title compound.

Workup

  1. temperatureheat
  2. temperatureat reflux for 18 hours
  3. customEvaporate the solvent in vacuo
  4. distillationpurify by distillation

Sources & evidence

ORD record
ord-8814d0d5766f4e18afa32a0fcc5b4ce4
Source dataset
uspto-grants-1993_06
Patent number
US05217964

Reaction notes

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