N-[3-bromo-5-(pyridine-3-carbonyl)-phenyl]-methanesulfonamide → N-[3-(1H-indol-4-yl)-5-(pyridine-3-carbonyl)-phenyl]-methanesulfonamide

HRID 158759Notes

Reaction equation

HRID 158759 reaction equation
[Br:1][c:2]1[cH:3][c:4]([NH:5][S:6]([CH3:7])(=[O:8])=[O:9])[cH:10][c:11]([C:12]([c:13]2[cH:14][n:15][cH:16][cH:17][cH:18]2)=[O:19])[cH:20]1.[n:21]1[cH:22][c:23]([C:27](=[O:28])[c:29]2[cH:30][c:31]([NH:54][S:55](=[O:56])(=[O:57])[CH3:58])[cH:32][c:33](-[c:35]3[c:36]4[cH:37][cH:38][n:39]([Si:44]([CH:45]([CH3:46])[CH3:47])([CH:48]([CH3:49])[CH3:50])[CH:51]([CH3:52])[CH3:53])[c:40]4[cH:41][cH:42][cH:43]3)[cH:34]2)[cH:24][cH:25][cH:26]1>>[n:21]1[cH:22][c:23]([C:27](=[O:28])[c:29]2[cH:30][c:31]([NH:54][S:55](=[O:56])(=[O:57])[CH3:58])[cH:32][c:33](-[c:35]3[c:36]4[cH:37][cH:38][nH:39][c:40]4[cH:41][cH:42][cH:43]3)[cH:34]2)[cH:24][cH:25][cH:26]1

Participants

3

Reactant 2

HCID 50994356N-[3-bromo-5-(pyridine-3-carbonyl)-phenyl]-methanesulfonamideHCID 50994434N-[3-(pyridine-3-carbonyl)-5-(1-triisopropylsilanyl-1H-indol-4-yl)-phenyl]-methanesulfonamide

Product 1

HCID 15602988N-[3-(1H-indol-4-yl)-5-(pyridine-3-carbonyl)-phenyl]-methanesulfonamide

Sources & evidence

ORD record
ord-a72f250a7e924f00859533bb2be859f3
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (9/10)

Reaction notes

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