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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1587613Generated: October 30, 2026

1alpha,3beta-Bis(methoxycarbonyloxy)pregna-5,7-diene-20-carbaldehyde → 1alpha,3beta-Bis(t-butyldimethylsilyloxy)-20-methylpregna-5,7-dien-21-ol

https://huagongshe.com/reaction/1587613

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1alpha,3beta-Bis(methoxycarbonyloxy)pregna-5,7-diene-20-carbaldehydeHCID 54367523—
Reactant1alpha,3beta-Bis(t-butyldimethylsilyloxy)pregna-5,7-diene-20-carbaldehydeHCID 54425982—
Product1alpha,3beta-Bis(t-butyldimethylsilyloxy)-20-methylpregna-5,7-dien-21-olHCID 5457202183.3%

Reaction Steps

The procedure of Example 1 was repeated except that 110 mg of 1α,3β-bis(t-butyldimethylsilyloxy)pregna-5,7-diene-20-carbaldehyde was used in lieu of 100 mg of 1α,3β-bis(methoxycarbonyloxy)pregna-5,7-diene-20-carbaldehyde to give 92 mg of 1α,3β-bis(t-butyldimethylsilyloxy)-20-methylpregna-5,7-dien-21-ol.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS05218109
Source datasetuspto-grants-1993_06
ORD IDord-dfb2a672cf784c1fba4efe2ddfa93249
Source noteuspto-grants-1993_06