HuagongsheHuagongshe Chemistry Print Report · For research reference only
1alpha,3beta-Bis(methoxycarbonyloxy)pregna-5,7-diene-20-carbaldehyde → 1alpha,3beta-Bis(t-butyldimethylsilyloxy)pregna-5,7-diene-20-carboxylic acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1alpha,3beta-Bis(methoxycarbonyloxy)pregna-5,7-diene-20-carbaldehyde | HCID 54367523 | — |
| Reactant | 1alpha,3beta-Bis(t-butyldimethylsilyloxy)pregna-5,7-diene-20-carbaldehyde | HCID 54425982 | — |
| Product | 1alpha,3beta-Bis(t-butyldimethylsilyloxy)pregna-5,7-diene-20-carboxylic acid | HCID 54107153 | 77.8% |
Reaction Steps
The procedure of Example 6 was repeated except that 140 mg of 1α,3β-bis(t-butyldimethylsilyloxy)pregna-5,7-diene-20-carbaldehyde was used in lieu of 120 mg of 1α,3β-bis(methoxycarbonyloxy)pregna-5,7-diene-20-carbaldehyde to give 112 mg of 1α,3β-bis(t-butyldimethylsilyloxy)pregna-5,7-diene-20-carboxylic acid.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05218109 |
| Source dataset | uspto-grants-1993_06 |
| ORD ID | ord-b62d9f568d6447a2ae369b9e0362804e |
| Source note | uspto-grants-1993_06 |