反应详情

To a solution of 0.85 g (4.7 mmol) of 3-propoxypicolinic acid dissolved in 35 ml of water was dropwise added, while stirring, a solution of 0.52 g (2.3 mmol) of zinc acetate.dihydrate dissolved in 2 ml of water. After the dropwise addition, the mixture was stirred at room temperature for 60 minutes. When left to stand in a refrigerator overnight, no crystal was obtained, and therefore, the mixture was subjected to concentration under a reduced pressure. The solid precipitated was recrystallized from ethanol to obtain 0.50 g of crystals (yield 47.6%).

1. additionwas dropwise added
2. additionAfter the dropwise addition
3. stirringthe mixture was stirred at room temperature for 60 minutes
4. waitWhen left
5. customto stand in a refrigerator overnight
6. customno crystal was obtained
7. concentrationthe mixture was subjected to concentration under a reduced pressure
8. customThe solid precipitated
9. customwas recrystallized from ethanol