(-)-Mandelic acid → HCID 131717976, compound

HRID 1587718Notes

Reaction equation

HRID 1587718 reaction equation
[CH3:1][N:2]1[C:10]2[C:5](=[CH:6][CH:7]=[CH:8][CH:9]=2)[C:4]([CH:11]([CH2:14][CH2:15][CH2:16][CH3:17])[CH2:12][NH2:13])=[CH:3]1.[C:18]([OH:28])(=[O:27])[C@@H:19]([C:21]1[CH:26]=[CH:25][CH:24]=[CH:23][CH:22]=1)[OH:20]>CCOCC>[C:18]([OH:28])(=[O:27])[CH:19]([C:21]1[CH:26]=[CH:25][CH:24]=[CH:23][CH:22]=1)[OH:20].[CH3:1][N:2]1[C:10]2[C:5](=[CH:6][CH:7]=[CH:8][CH:9]=2)[C:4]([CH:11]([CH2:14][CH2:15][CH2:16][CH3:17])[CH2:12][NH2:13])=[CH:3]1

Participants

4

Reactant 2

HCID 11914(-)-Mandelic acidHCID 10561466HCID 10561466, compound

Product 1

HCID 131717976HCID 131717976, compound

Reagents, catalysts & solvents 1

HCID 3283Diethyl EtherSolvent

Conditions

Temperature
20 °C

Procedure

24 g (0.104 mol) of 2-(1-methyl-3-indolyl)hexylamine, prepared under the conditions of Example 1, and 15.8 g (0.104 mol) of (R)-(-)-mandelic acid are dissolved in 600 cm3 of ether; after 3 hours of stirring at 20° C., the solid formed is drained and dried (m.p. 92°-100° C., quantity=23.1 g).

Workup

  1. customthe solid formed
  2. customdried (m.p. 92°-100° C., quantity=23.1 g)

Sources & evidence

ORD record
ord-e2b95f8343e84313888f7e6693c7ee60
Source dataset
uspto-grants-1993_06
Patent number
US05219859

Reaction notes

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