Bromine → HCID 19756155, compound

HRID 1587721Notes

Reaction equation

HRID 1587721 reaction equation
[OH:1][C:2]1[C:12]([OH:13])=[CH:11][CH:10]=[C:4]2[C:5]([NH:7][C:8](=[O:9])[C:3]=12)=[O:6].[Br:14]Br>C(O)(=O)C>[Br:14][C:11]1[CH:10]=[C:4]2[C:5]([NH:7][C:8](=[O:9])[C:3]2=[C:2]([OH:1])[C:12]=1[OH:13])=[O:6]

Participants

4

Reactant 2

HCID 24408BromineHCID 166409824,5-dihydroxy-2,3-dihydro-1H-isoindole-1,3-dione

Product 1

HCID 19756155HCID 19756155, compound

Reagents, catalysts & solvents 1

HCID 176Acetic AcidSolvent

Procedure

3,4-Dihydroxyphthalimide (Example 4e) was heated with bromine in acetic acid for about 6 hours to give 5-bromo-3,4-dihydroxyphthalimide which was subsequently treated in a manner similar to Example 1f)-h).

Sources & evidence

ORD record
ord-85cbb9ea8f2143b78fc3de65274e5ded
Source dataset
uspto-grants-1993_06
Patent number
US05219848

Reaction notes

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