反应详情

A mixture of 0.8 g of 1-(2-n-propylphenyliminomethyl)-nitroiminoimidazolidine, 0.42 g of 2-chloro-5-chloromethylpyridine, 0.36 g of potassium carbonate and 8 ml of acetonitrile were refluxed under heating conditions for 4 hours. The reaction mixture was evaporated and purified by column chromatography [silica gel, eluent: hexane-ethyl acetate (1:2)] to give 0.32 g of 1-(2-chloropyridin-5-ylmethyl)-2-nitroimino-3-(2-propylphenyliminomethyl)imidazolidine.

1. temperaturewere refluxed under heating conditions for 4 hours
2. customThe reaction mixture was evaporated
3. custompurified by column chromatography [silica gel, eluent: hexane-ethyl acetate (1:2)]