Dimethyl Sulfoxide → HCID 53827712, compound

Participants

Reaction Conditions

Reaction Steps

A mixture of 3.00 g of 1-(4-acetylphenyliminomethyl)-2-nitroiminoimidazolidine, 2.12 g of 2-chloro-5-chloromethylpyridine, 3.01 g of potassium carbonate, and 7 ml of DMSO was agitated at 60° C. for 1 hour. The reaction mixture was poured into water, extracted with ethyl acetate, washed with water, dried and evaporated to obtain an oily residue. To the resultant oily residue was added ethyl acetate, followed by separation of the resultant crystals by filtration and drying to give 1.73 g of 1-(2-chloropyridine-5-ylmethyl)-2-nitroimino-3-(4-acetylphenyliminomethyl)imidazolidine.

Provenance & Evidence