1,3-Dimethyl-2-imidazolidinone → HCID 136331480, compound

Participants

Reaction Steps

A mixture of 60.6 g of 3,4-dimethylaniline, 200 g of ethyl orthoformate and 0.05 g of sulfuric acid was placed in a reactor equipped with Dean's stark tube and agitated at 140° to 165° C. for about 1 hour. After concentration of the reaction solution under reduced pressure, 45 g of nitroiminoimidazolidine and 70 g of 1,3-dimethyl-2-imidazolidinone were added and agitated at 140° to 160° C. for 2 hours. The reaction mixture was poured into 200 ml of a saturated saline solution, to which 150 ml of ethyl acetate was added. The resultant crystals were collected by filtration, washed with ethyl acetate and dried to give 40.2 g of 1-(3,4-dimethylphenyliminomethyl)-2-nitroiminoimidazolidine.

Provenance & Evidence