Tert-Butyl hypochlorite → HCID 86746971, compound

HRID 1587760Notes

Reaction equation

HRID 1587760 reaction equation
[CH3:1][O:2][C:3]([C@@H:5]1[CH2:19][C@H:18]2[C@@H:8]([CH2:9][C:10]3[C:20]4[C:13](=[CH:14][CH:15]=[CH:16][C:17]2=4)[NH:12][C:11]=3[CH2:21]N2CCOCC2)[N:7]([CH2:28][CH:29]2[CH2:31][CH2:30]2)[CH2:6]1)=[O:4].C([O:36]Cl)(C)(C)C>>[CH3:1][O:2][C:3]([C@@H:5]1[CH2:19][C@H:18]2[C@@H:8]([CH2:9][C:10]3[C:20]4[C:13](=[CH:14][CH:15]=[CH:16][C:17]2=4)[NH:12][C:11]=3[CH:21]=[O:36])[N:7]([CH2:28][CH:29]2[CH2:31][CH2:30]2)[CH2:6]1)=[O:4]

Participants

3

Reactant 2

HCID 521297Tert-Butyl hypochloriteHCID 67885454HCID 67885454, compound

Product 1

HCID 86746971HCID 86746971, compound

Procedure

As described above, the aldehyde is prepared from the 6-cyclopropylmethyl-2-morpholinomethyl-8beta-ergoline-carboxylic acid methyl ester by oxidation with tert-butylhypochlorite. All the ergoline-aldehydes alkylated in 6-position are used as crude products in the Wittig reaction.

Workup

  1. customare used as crude products in the Wittig reaction

Sources & evidence

ORD record
ord-d3ce86b3d2824563a4c62dc247e5e65c
Source dataset
uspto-grants-1993_06
Patent number
US05219862

Reaction notes

Loading…