HCID 67768689, compound → HCID 14822456, compound

Participants

Reaction Steps

0.83 g of 6-n-propyl-2-vinyl-8beta-ergoline-carboxylic acid methyl ester (2.5 mmol) is dissolved in 50 ml of methanol, mixed with 80 g of palladium/carbon 10% and hydrogenated at standard pressure and room temperature. After 10 minutes, the absorption is completed, it is filtered off and the filtrate is concentrated by evaporation. The residue is crystallized, yield of 800 mg (94% of theory) [α]D =-63° (0.1% in chloroform).

Provenance & Evidence