HCID 67885617, compound → HCID 14822417, compound

HRID 1587763Notes

Reaction equation

HRID 1587763 reaction equation
CO[CH2:3][C:4]1[NH:18][C:17]2[C:19]3[C:5]=1[CH2:6][C@@H:7]1[C@@H:12]([C:13]=3[CH:14]=[CH:15][CH:16]=2)[CH2:11][C@@H:10]([CH2:20][C:21]#[N:22])[CH2:9][N:8]1[CH2:23][CH2:24][CH3:25]>C(Cl)(Cl)Cl>[CH3:3][C:4]1[NH:18][C:17]2[C:19]3[C:5]=1[CH2:6][C@@H:7]1[C@@H:12]([C:13]=3[CH:14]=[CH:15][CH:16]=2)[CH2:11][C@@H:10]([CH2:20][C:21]#[N:22])[CH2:9][N:8]1[CH2:23][CH2:24][CH3:25]

Participants

3

Reactant 1

HCID 67885617HCID 67885617, compound

Product 1

HCID 14822417HCID 14822417, compound

Reagents, catalysts & solvents 1

HCID 6212ChloroformSolvent

Procedure

(2-methoxymethyl-6-n-propyl-8beta-ergolinyl)-acetonitrile, yield 91%, [α]D =-91° (0.5% in chloroform).

Sources & evidence

ORD record
ord-86135b65041b4ca3a17e3cd0eddb29c6
Source dataset
uspto-grants-1993_06
Patent number
US05219862

Reaction notes

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