HuagongsheHuagongshe Chemistry Print Report · For research reference only
Sodium cyanoborohydride → 3-Chloro-4,5-dihydro-7-[3-(trifluoromethyl)phenyl]pyrazolo[1,5-a]pyrimidine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Sodium cyanoborohydride | HCID 5003444 | — |
| Reactant | 3-Chloro-7-(alpha,alpha,alpha-trifluoro-m-tolyl)pyrazolo[1,5-a]pyrimidine | HCID 19756220 | — |
| Solvent | Acetic Acid | HCID 176 | — |
| Product | 3-Chloro-4,5-dihydro-7-[3-(trifluoromethyl)phenyl]pyrazolo[1,5-a]pyrimidine | HCID 136183858 | — |
Reaction Steps
A 13.3 g portion of 3-chloro-7-[3-(trifluoromethyl)phenyl)pyrazolo[1,5-a]pyrimidine and 7 g of sodium cyanoborohydride in 150 ml of acetic acid, were reacted as described in Example 1, giving 6.7 g of 3-chloro-4,5-dihydro-7-[3-(trifluoromethyl) phenyl]pyrazolo[1,5-a]pyrimidine.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05219857 |
| Source dataset | uspto-grants-1993_06 |
| ORD ID | ord-804ba2c409dd42e7a95612b93671bd09 |
| Source note | uspto-grants-1993_06 |