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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1587785Generated: October 26, 2026

1-(3-Chlorobenzyl)piperazine → 7-(4-Chlorophenyl)-4-[[4-[(3-chlorophenyl)methyl]-1-piperazinyl]acetyl]-4,5-dihydro-6-methylpyrazolo[1,5-a]pyrimidine-3-carbonitrile. dihydrochloride

https://huagongshe.com/reaction/1587785

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1-(3-Chlorobenzyl)piperazineHCID 764727—
Reactant4-(Chloroacetyl)-7-(4-chlorophenyl)-4.5-dihydro-6-methylpyrazolo[1,5-a]pyrimidine-3-carbonitrileHCID 15101089—
Product7-(4-Chlorophenyl)-4-[[4-[(3-chlorophenyl)methyl]-1-piperazinyl]acetyl]-4,5-dihydro-6-methylpyrazolo[1,5-a]pyrimidine-3-carbonitrile. dihydrochlorideHCID 131716673—

Reaction Steps

The above compound was prepared by the reaction of 4-(3-chlorophenyl)methylpiperazine with the compound of Example 14 by the methods of Examples 16 then 77, mp 250° C. (with sintering).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS05219857
Source datasetuspto-grants-1993_06
ORD IDord-bdfd618f33b14f19bb3411d118e80fcb
Source noteuspto-grants-1993_06