HuagongsheHuagongshe Chemistry Print Report · For research reference only
1-Benzylpiperazine → 4,5-Dihydro-6-methyl-4[[4-(phenylmethyl)-1-piperazinyl]acetyl]-7-[3-(trifluoromethyl)phenyl]pyrazolo[1,5-a]pyrimidine-3-carbonitrile, dihydrochloride
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1-Benzylpiperazine | HCID 75994 | — |
| Reactant | 4-(Chloroacetyl)-4,5-dihydro-6-methyl-7-[3-(trifluoromethyl)phenyl]pyrazolo[1,5-a]-pyrimidine-3-carbonitrile | HCID 15101085 | — |
| Product | 4,5-Dihydro-6-methyl-4[[4-(phenylmethyl)-1-piperazinyl]acetyl]-7-[3-(trifluoromethyl)phenyl]pyrazolo[1,5-a]pyrimidine-3-carbonitrile, dihydrochloride | HCID 131716668 | — |
Reaction Steps
The above compound was prepared by the reaction of N-benzylpiperazine with the compound of Example 10 by the methods of Example 16 then 77, mp 204°-206° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05219857 |
| Source dataset | uspto-grants-1993_06 |
| ORD ID | ord-d5c8d9c38636472e9b794f179cdc6dae |
| Source note | uspto-grants-1993_06 |