Acetone → HCID 19756570, compound

HRID 1587817Notes

Reaction equation

HRID 1587817 reaction equation
[C:1]1([C:7]#[C:8][CH2:9][O:10][C:11]2[CH:12]=[C:13]([C:17]([OH:21])([CH3:20])[CH2:18][OH:19])[CH:14]=[N:15][CH:16]=2)[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1.[CH3:22][C:23]([CH3:25])=O>>[CH3:22][C:23]1([CH3:25])[O:21][C:17]([CH3:20])([C:13]2[CH:14]=[N:15][CH:16]=[C:11]([O:10][CH2:9][C:8]#[C:7][C:1]3[CH:2]=[CH:3][CH:4]=[CH:5][CH:6]=3)[CH:12]=2)[CH2:18][O:19]1

Participants

3

Reactant 2

HCID 180AcetoneHCID 19756618HCID 19756618, compound

Product 1

HCID 19756570HCID 19756570, compoundYield 76%

Procedure

Using the procedure described in Example 1, 2-[5-(3-phenylprop-2-ynyloxy)pyrid-3-yl]propane-1,2-diol was reacted with acetone to give 2,2,4-trimethyl-4-[5-(3-phenylprop-2-ynyloxy)pyrid-3-yl]-1,3-dioxolane in 76% yield, as an oil.

Sources & evidence

ORD record
ord-230023a6702442fe94cd3574efd648bb
Source dataset
uspto-grants-1993_06
Patent number
US05219881

Reaction notes

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