HuagongsheHuagongshe Chemistry Print Report · For research reference only
Acetic acid, 2-oxo-, methyl ester → Methyl 3-[2-(4-carbomethoxyphenyl)-1-methylethyl]-5-(2-trifluoromethyl-thiazol-4-yl)-2-oxazolidine carboxylate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Acetic acid, 2-oxo-, methyl ester | HCID 70205 | — |
| Reactant | N-[2-(4-Carbomethoxyphenyl)-1-methylethyl]-2-hydroxy-2-(2-trifluoromethyl-thiazol-4-yl)ethanamine | HCID 19974173 | — |
| Product | Methyl 3-[2-(4-carbomethoxyphenyl)-1-methylethyl]-5-(2-trifluoromethyl-thiazol-4-yl)-2-oxazolidine carboxylate | HCID 19974308 | — |
Reaction Steps
Prepared analogously to Example 18 by reaction of N-[2-(4-carbomethoxyphenyl)-1-methylethyl]-2-hydroxy-2-(2-trifluoromethyl-thiazol-4-yl)ethanamine with methyl glyoxylate.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05219852 |
| Source dataset | uspto-grants-1993_06 |
| ORD ID | ord-e73e9d1ef8904efbbe48e7da77cab665 |
| Source note | uspto-grants-1993_06 |