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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1587928Generated: October 31, 2026

2-(2-Trifluoromethyl-thiazol-4-yl)morpholine → N-[2-(4-(2-Carbomethoxy-1-methylethenyl) phenyl)-1-methylethyl]-2-(2-trifluoromethyl-thiazol-4-yl)morpholine

https://huagongshe.com/reaction/1587928

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-(2-Trifluoromethyl-thiazol-4-yl)morpholineHCID 19974265—
Reactant1-[4-(2-Carbomethoxy-1-methylethenyl)phenyl]propan-2-oneHCID 54548003—
ProductN-[2-(4-(2-Carbomethoxy-1-methylethenyl) phenyl)-1-methylethyl]-2-(2-trifluoromethyl-thiazol-4-yl)morpholineHCID 54361252—

Reaction Steps

Prepared analogously to Example 13 by reaction of 2-(2-trifluoromethyl-thiazol-4-yl)morpholine with 1-[4-(2-carbomethoxy-1-methylethenyl)phenyl]propan-2-one followed by purification of the base on a silica gel column using chloroform/ethyl acetate=19:1 as eluant.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS05219852
Source datasetuspto-grants-1993_06
ORD IDord-80ae3505fb7c4d96810a47e3eadb8b83
Source noteuspto-grants-1993_06