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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1587950Generated: October 31, 2026

Diboron → HCID 14391988, compound

https://huagongshe.com/reaction/1587950

Reaction equation

Participants

RoleNameHCIDCharge
ReactantDiboronHCID 6328200—
ReactantN-[2-(4-Carbomethoxymethoxyphenyl)-1-methylethyl]-2-(2-trifluoromethyl-thiazol-4-yl)morpholin-5-oneHCID 19974202—
SolventTetrahydrofuranHCID 8028—
ProductHCID 14391988HCID 14391988—

Reaction Steps

Prepared by analogy to Example 74b by reaction of N-[2-(4-carbomethoxymethoxyphenyl)-1-methylethyl]-2-(2-trifluoromethyl-thiazol-4-yl)morpholin-5-one (diastereomer B) with diborane in tetrahydrofuran, followed by purification of the base on a silica gel column using toluene/ethyl acetate=8:2 as eluant.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS05219852
Source datasetuspto-grants-1993_06
ORD IDord-8dca1cc90a0f4610821bd9ddb7dd03b2
Source noteuspto-grants-1993_06