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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1587977Generated: October 31, 2026

Potassium Bicarbonate → HCID 14347785, compound

https://huagongshe.com/reaction/1587977

Reaction equation

Participants

RoleNameHCIDCharge
ReactantPotassium BicarbonateHCID 516893—
ReactantHCID 10978660HCID 10978660—
ReactantN-[2-(4-Carbomethoxymethoxyphenyl)-1-methylethyl]-2-hydroxy-2-(2-trifluoromethyl-thiazol-4-yl)ethanamineHCID 14347763—
SolventAcetoneHCID 180—
ProductHCID 14347785HCID 14347785—

Reaction Steps

from N-[2-(4-carbomethoxymethoxyphenyl)-1-methylethyl]-2-hydroxy-2-(2-trifluoromethyl-thiazol-4-yl)ethanamine (pair of diastereomers A) with 2-trifluoromethyl-4-bromoacetyl-thiazole and potassium hydrogen carbonate in acetone.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS05219852
Source datasetuspto-grants-1993_06
ORD IDord-27d3359ea4a44592855d59281817b842
Source noteuspto-grants-1993_06