(3-Methoxyphenyl)acetonitrile → HCID 10998885, compound
Reaction equation
[CH3:1][O:2][C:3]1[CH:4]=[C:5]([CH2:9][C:10]#[N:11])[CH:6]=[CH:7][CH:8]=1.Cl.Cl[CH2:14][CH2:15][CH2:16][N:17]([CH3:19])[CH3:18]>>[CH3:18][N:17]([CH3:19])[CH2:16][CH2:15][CH2:14][CH:9]([C:5]1[CH:6]=[CH:7][CH:8]=[C:3]([O:2][CH3:1])[CH:4]=1)[C:10]#[N:11]Participants
3
Procedure
reacting 3-methoxybenzeneacetonitrile with 3-chloro-N,N-dimethylpropanamine, monohydrochloride in the presence of a base to obtain α-[3-(dimethylamino)propyl]-3-methoxybenzeneacetonitrile
Sources & evidence
- ORD record
- ord-7126a7da0dae4343890f0f212d3f06bc
- Source dataset
- uspto-grants-1993_06
- Patent number
- US05220019
Reaction notes
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