HuagongsheHuagongshe Chemistry Print Report · For research reference only
3-Nitro-N-(2-propylsulfonyl)phenylcarboxamide → 3-Amino-N-(isopropylsulfonyl)benzamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 3-Nitro-N-(2-propylsulfonyl)phenylcarboxamide | HCID 23353152 | — |
| Catalyst | Palladium | HCID 23938 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | 3-Amino-N-(isopropylsulfonyl)benzamide | HCID 18957778 | 57.5% |
Reaction Steps
3-Nitro-N-(2-propylsulfonyl)phenylcarboxamide (0.6 g) was dissolved in 30 ml of ethanol, treated with 300 mg of 10% palladium/carbon catalyst, and hydrogenated on a Parr apparatus at 30 psi for 15 minutes. The reaction mixture was filtered through Celite and concentrated to give the title compound (307 mg) as a solid.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05220018 |
| Source dataset | uspto-grants-1993_06 |
| ORD ID | ord-4dfd9ea3f61f4ed9b2a31e111372e20e |
| Source note | uspto-grants-1993_06 |