Ethylenediamine → HCID 178510879, compound

HRID 1588188Notes

Reaction equation

HRID 1588188 reaction equation
Br[C:2]1[N:3]([C:11]2[N:12]=[CH:13][N:14]=[C:15]([OH:18])[C:16]=2[N:17]=1)[C@@H:4]1[O:10][C@H:7]([CH2:8][OH:9])[CH2:6][CH2:5]1.[CH2:19](N)[CH2:20][NH2:21]>>[NH2:21][CH2:20][CH2:19][C@@:4]1([N:3]2[C:11]3[N:12]=[CH:13][N:14]=[C:15]([OH:18])[C:16]=3[N:17]=[CH:2]2)[O:10][C@H:7]([CH2:8][OH:9])[CH2:6][CH2:5]1

Participants

3

Reactant 2

HCID 3301EthylenediamineHCID 178520960HCID 178520960, compound

Product 1

HCID 178510879HCID 178510879, compound

Procedure

The product from step 1 can then be reacted with ethylenediamine to give 8-(2-aminoethyl -2',3'-dideoxyinosine (8-AE-ddI) (Reaction B).

Sources & evidence

ORD record
ord-163dba5e9a234baf879fe90b1a36124e
Source dataset
uspto-grants-1993_06
Patent number
US05221611

Reaction notes

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