HCID 20079491, compound → HCID 15053113, compound

Participants

Reaction Steps

A suspension of 5-[(4-nitro-3-pyridinyl)oxy]-1H-indole, N5 -oxide (10 g) in 250 ml ethanol containing 0.4 g PtO2 was hydrogenated at 50 psi for 25 hours and thereafter filtered through Celite and concentrated to 9 g oil. This oil was purified by HPLC (silica, 10% methanol in ethyl acetate) to give 3.5 g solid. This solid was recrystallized from acetonitrile to give 2.4 g crystals, m.p. 170°-172°.

Provenance & Evidence