3-Fluorobenzoic Acid → HCID 54093775, compound

HRID 1588288Notes

Reaction equation

HRID 1588288 reaction equation
[NH:1]=[C:2]1[NH:6][C:5]([C:11]([F:14])([F:13])[F:12])([C:7]([F:10])([F:9])[F:8])[C:4](=[C:15]([F:20])[C:16]([F:19])([F:18])[F:17])[S:3]1.C1(N=C=NC2CCCCC2)CCCCC1.[F:36][C:37]1[CH:38]=[C:39]([CH:43]=[CH:44][CH:45]=1)[C:40](O)=[O:41]>ClCCl>[F:36][C:37]1[CH:38]=[C:39]([CH:43]=[CH:44][CH:45]=1)[C:40]([NH:1][C:2]1[S:3][C:4](=[C:15]([F:20])[C:16]([F:17])([F:18])[F:19])[C:5]([C:7]([F:10])([F:9])[F:8])([C:11]([F:12])([F:13])[F:14])[N:6]=1)=[O:41]

Participants

5

Reactant 3

HCID 99683-Fluorobenzoic AcidHCID 10868DicyclohexylcarbodiimideHCID 178508427HCID 178508427, compound

Product 1

HCID 54093775HCID 54093775, compound

Reagents, catalysts & solvents 1

HCID 6344DichloromethaneSolvent2×

Procedure

In dichloromethane (10 ml) were dissolved 2-imino-4,4-bis(trifluoromethyl)-5-(tetrafluoroethylidene)-1,3-thiazolidine (1.0 g) and dicyclohexylcarbodiimide (2.4 g), and a solution of 3-fluorobenzoic acid (1.6 g) dissolved in dichloromethane (10 ml) was gradually added thereto and the mixture was stirred at room temperature for 3 hours.

Workup

  1. additionwas gradually added

Sources & evidence

ORD record
ord-918e187bc4f4478a9defa5871a9a3abf
Source dataset
uspto-grants-1993_06
Patent number
US05221685

Reaction notes

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