Water → HCID 54043278, compound

HRID 1588298Notes

Reaction equation

HRID 1588298 reaction equation
[Cl:1][C:2]1[CH:11]=[C:10]([Cl:12])[CH:9]=[CH:8][C:3]=1[O:4][CH2:5][CH2:6]Br.C(=O)([O-])[O-].[Na+].[Na+].[Cl:19][C:20]1[CH:21]=[C:22]([CH:25]=[CH:26][CH:27]=1)[CH2:23][NH2:24].O>C(O)C>[Cl:19][C:20]1[CH:21]=[C:22]([CH:25]=[CH:26][CH:27]=1)[CH2:23][NH:24][CH2:6][CH2:5][O:4][C:3]1[CH:8]=[CH:9][C:10]([Cl:12])=[CH:11][C:2]=1[Cl:1]

Participants

6

Reactant 4

HCID 962WaterHCID 10340Sodium CarbonateHCID 77802Benzenemethanamine, 3-chloro-HCID 1388811-(2-Bromoethoxy)-2,4-dichlorobenzene

Product 1

HCID 54043278HCID 54043278, compound

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent

Procedure

2.70 Grams (10.0 mmol) of 2-(2,4-dichlorophenoxy)ethyl bromide was dissolved in 30 ml of ethanol, followed by the addition of 1.06 g (10.0 mmol) of anhydrous sodium carbonate and 4.25 g (30.0 mmol) of 3-chlorobenzylamine. The mixture was refluxed for 6 hours on an oil bath. After cooling, the reaction mixture was poured into 100 ml of water and was extracted with chloroform (20 ml×3).

Workup

  1. temperatureThe mixture was refluxed for 6 hours on an oil bath
  2. temperatureAfter cooling
  3. extractionwas extracted with chloroform (20 ml×3)

Sources & evidence

ORD record
ord-75f20b10ef214bce92e23241330d85a7
Source dataset
uspto-grants-1993_06
Patent number
US05221694

Reaction notes

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