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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1588307Generated: November 4, 2026

2-(3-Pyrrolidinyl)benzenemethanamine → 7-[3-[2-(Aminomethyl)phenyl]-1-pyrrolidinyl]-1-cyclopropyl-6-fluoro-1,4-dihydro-8-methoxy-4-oxo-3-quinolinecarboxylic acid

https://huagongshe.com/reaction/1588307

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-(3-Pyrrolidinyl)benzenemethanamineHCID 15288428—
ReactantHCID 178493651HCID 178493651—
Product7-[3-[2-(Aminomethyl)phenyl]-1-pyrrolidinyl]-1-cyclopropyl-6-fluoro-1,4-dihydro-8-methoxy-4-oxo-3-quinolinecarboxylic acidHCID 15288429—

Reaction Steps

Starting from difluoroborane 1-cyclopropyl-6,7-difluoro-1,4-dihydro-8-methoxy-4-oxo-3-quinolinecarboxylate (1.13 g, 3.3 mmol) and 2-(3-pyrrolidinyl)benzenemethanamine, a procedure analogous to that given in Example 1, provided the fluoroborate ester of the title compound.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS05221676
Source datasetuspto-grants-1993_06
ORD IDord-d560012c91f94e5985b3b2f2c8125a17
Source noteuspto-grants-1993_06