Unoprostone isopropyl ester → Dinoprost

HRID 1588405Notes

Reaction equation

HRID 1588405 reaction equation
CC[CH2:3][CH2:4][CH2:5][CH2:6][CH2:7][C:8]([CH2:10][CH2:11][C@@H:12]1[C@@H:16]([CH2:17]/[CH:18]=[CH:19]/[CH2:20][CH2:21][CH2:22][C:23]([O:25]C(C)C)=[O:24])[C@@H:15]([OH:29])[CH2:14][C@H:13]1[OH:30])=[O:9].O[C@@H]1C[C@H](O)[C@H](C/C=C\CCCC(OC(C)C)=O)[C@H]1CCC(=O)CCCCCCC>>[OH:30][C@@H:13]1[CH2:14][C@H:15]([OH:29])[C@H:16]([CH2:17]/[CH:18]=[CH:19]\[CH2:20][CH2:21][CH2:22][C:23]([OH:25])=[O:24])[C@H:12]1/[CH:11]=[CH:10]/[C@@H:8]([OH:9])[CH2:7][CH2:6][CH2:5][CH2:4][CH3:3]

Participants

3

Reactant 2

HCID 5282175Unoprostone isopropyl esterHCID 6440208HCID 6440208, compound

Product 1

HCID 5280363Dinoprost

Procedure

13,14-dihydro-15-keto-20-ethyl-PGF2 α isopropyl ester is isopropyl(Z)-7-[(1R,2R,3R,5S)-3,5-dihydroxy-2-{3-oxo-1-decyl}cyclopentyl]-hept-5-enoate;

Sources & evidence

ORD record
ord-9416798fc379474097a7b8bae7ea6e65
Source dataset
uspto-grants-1993_06
Patent number
US05221763

Reaction notes

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