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Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
HRID 1588512생성일: 2026년 10월 26일

p-Methylphenethylamine → N-cyano-N'-[2-(4-methylphenyl)ethyl]-2-pyridinecarboximidamide

https://huagongshe.com/reaction/1588512

반응식

참여 물질

역할이름HCID투입량
반응물p-MethylphenethylamineHCID 76751—
반응물2-Pyridinecarboximidic acid, N-cyano-, methyl esterHCID 10012189—
용매MethanolHCID 887—
생성물N-cyano-N'-[2-(4-methylphenyl)ethyl]-2-pyridinecarboximidamideHCID 1973455793.5%

반응 단계

Methyl N-cyano-2-pyridinecarboximidate (0.50 g, 3.1 mmol) was dissolved in methanol (10 ml), 2-(p-tolyl)ethylamine (0.47 g, 3.5 mmol) was added, and the resulting mixture was stirred at room temperature for 1 hour. After the reaction was completed, the reaction solution was concentrated under reduced pressure, and the residue thus obtained was crystallized from methanoldiethyl ether to give the title compound (0.76 g, 2.9 mmol, yield: 93%) as colorless crystals.

출처 및 근거

DOI10.6084/m9.figshare.5104873.v1
특허 번호US05223508
출처 데이터셋uspto-grants-1993_06
ORD IDord-147b489c79434471beedc2ae3c01f153
출처 메모uspto-grants-1993_06